The NIMML Institute is a 501 (c) (3) non-profit public charity foundation focused on a transdisciplinary, team-science approach to precision medicine at the interface of immunology, inflammation, and metabolism. The NIMML Institute team has led numerous large-scale transdisciplinary projects and is dedicated to solving important societal problems by combining the expertise of immunologists, computational biologists, toxicologists, modelers, translational researchers, and molecular biologists. The central integrative theme of NIMML Institute is the view of the immune system as a massively and dynamically interacting system and the application of novel advanced computational methods to unravel its complexity and accelerate the discovery and characterization of novel pathways to enable the development of new classes of therapeutics for autoimmune, infectious, and chronic inflammatory diseases.

NIMML History

NIMML was founded in 2002 under the guidance of Dr. Bassaganya-Riera and Dr. Hontecillas. The NIMML Institute is committed to transdisciplinary, team-science approaches with a personalized medicine focus at the interface of immunology, inflammation, and metabolism. The NIMML research programs incorporate drug development, nutritional immunology, immunometabolism, computational immunology, and clinical and translational research in autoimmune, infectious, and chronic inflammatory diseases. The scope of NIMML’s research ranges from in silico and in vitro studies to mechanistic, translational and Phase 1-4 clinical trials.

The NIMML research has pioneered platforms applying high-throughput computational, experimental immunology techniques, and system biology approaches in translational immunology research and discovery. Through the NIAID-funded Center for Modeling Immunity to Enteric Pathogens under the Modeling Immunity for Biodefense (MIB) program, the NIMML applied advanced computational approaches to analyze high-dimensional, high-throughput datasets, model and simulate human immunology systems and help immunologists conduct in silico experiments to develop a more mechanistic experimental design, validate hypotheses and save significant time and laboratory cost.

Dr. Josep Bassaganya-Riera President, Founding Director & Distinguished Professor

Dr. Josep Bassaganya-Riera is the President and Founding Director of the NIMML Institute, a 501 (c)(3) public charity foundation. He is an innovator, thought leader, and serial entrepreneur, with more than 20 years of R&D experience in the interface of immunology and advanced computational modeling. As a Distinguished Professor, he has published over 200 peer-reviewed articles, book chapters and books on the acceleration of biopharmaceutical development, bioinformatics, and computational immunology, and he has contributed 50 patents in immunology and autoimmune disease treatment. He has founded 3 award-winning Companies (Landos Biopharma, Pervida and Biotherapeutics), raising over $200 million in non-dilutive and equity financing rounds. He served as the Director of the NIH-funded Center for Modeling Immunity to Enteric Pathogens under the modeling immunity for biodefense (MIB) program. Through its corporate culture, encapsulated in 4 pillars: be bold and decisive, never give up, be solution-oriented and do the impossible, these values empower NIMML Institute members to think outside the box to achieve creative and innovative solutions that promote technological innovation.

Selected Publications

In The News



Our Mission

To comprehensively and systematically characterize mechanisms of action underlying infectious, metabolic and autoimmune diseases; The NIMML Institute will translate this new scientific knowledge to identify new therapeutic targets and develop innovative therapeutics for human diseases that are safer and more effective.

Our Vision

To become a world-leading transdisciplinary research institute that combines advanced computational methods with preclinical, translational and clinical research and development.

Our Values

Be bold and decisive in solving the world’s most pressing challenges.

Never give up in finding disease treatments.

Be solution-oriented in the face of problems.

Do the Impossible to address the unmet needs of patients.

Open positions

What NIMML Students Say

"Working at NIMML is a unique experience because of the strong focus on team science. We have individuals from many different backgrounds with many different strengths all working together on projects. This fosters not only wonderful interpersonal dynamics but also very comprehensive and novel research that otherwise wouldn't be attainable."

- Kristin Eden

Please email us at jbassaga@nimml.org if you would like to discuss the possibility of contributing financial support for our research, or if you are ready to contribute a tax-deductible donation.